Influence of level of serum uric acid on prognosis in elderly patients with chronic heart failure
HAN Zhen
LI Yuan
XU Gui-dong
CHEN Lu
WANG Xi
MA Xue-xing
Abstract:Objective To discuss the influence of level of serum uric acid (UA) on prognosis in elderly patients with chronic heart failure (CHF).Methods CHF patients (n=258, male 118 and female 140) were continuously chosen from the Northern Area of Department of Cardiovascular Diseases of Suzhou Municipal Hospital from Jan. 2014 to Jun. 2015. All patients were divided, according to level of serum UA, into control group (n=121) and high UA group (n=137). The clinical data were collected including past medical history and laboratory test indexes, and all patients were followed up for 1 y.Results The levels of serum creatinine (SCr), UA and B-type natriuretic peptide (BNP) increased significantly in high UA group compared with control group (allP<0.05). After followed up for 1 y, the incidence rates of renal insufficiency (32.85%vs. 17.36%), new-onset atrial fibrillation (11.68%vs. 4.13%) and hyperkalemia (9.45%vs. 2.45%) were significantly higher in high UA group than those in control group (allP<0.05).Conclusion The incidence rates of renal insufficiency, new-onset atrial fibrillation and hyperkalemia are higher and prognosis is poor in CHF patients with higher level of serum UA.
Keywords:Serum uric acidAgednessChronic heart failurePrognosis
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 603-604,608 )