Correlation between platelet and lymphocyte ratio and severity of coronary artery lesions in patients with non-ST-segment elevation myocardial infarction
GUO Ying-jie
NING Bin
GE Hui-juan
ZHUANG Xiao-sai
Abstract:Objective To study the correlation between platelet and lymphocyte ratio (PLR) and severity of coronary artery lesions in patients with non-ST-segment elevation myocardial infarction (NSTEMI).Methods NSTEMI patients (n=92) were chosen as NSTEMI group from the Department of Cardiovascular Diseases of People's Hospital of Fuyang City from Feb. 2013 to Dec. 2015, and given examination of coronary angiography (CAG) and the results were graded by using SYNTAX scoring system. At the same time, the patients with suspected coronary heart disease and normal CAG results (n=82) were chosen as control group. The counts of peripheral venous platelet and lymphocytes were detected and PLR was calculated in all patients. The level of PLR was compared between 2 groups, and correlation between PLR and SYNTAX scores of severity of coronary artery lesion was analyzed.Results The level of PLR was significantly lower in control group than that in NSTEMI group (P<0.01), and PLR was positively correlated to SYNTAX scores (r=0.522,P<0.01). Logistic regression analysis showed that PLR was an independent predictive factor for higher SYNTAX scores of coronary artery lesions in NSTEMI patients (OR=1.018, 95%CI: 1.006-1.029,P<0.01).Conclusion The level of PLR increases significantly, and PLR is correlated to the severity of coronary artery lesions in NSTEMI patients, which can be taken as a simple method for predicting coronary artery lesions.
Keywords:PlateletLymphocyteMyocardial infarction
Publication Date:2017-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 600-602 )