Appraisal value of heart failure echocardiography index and N-terminal pro-brain natriuretic peptide to heart function in patients with chronic heart failure
TIAN Gui-fang
YANG Xiu-ling
DAI Yan-yan
WEI Chang-zheng
REN Zhan-ling
Abstract：Objective To investigate the appraisal value of heart failure echocardiography index (HFEI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) to heart function in patients with chronic heart failure (CHF). Methods CHF patients (n=92) were chosen (CHF group) from the Fourth People's Hospital of Langfang City from Jan. 2015 to June 2016, and then divided, according to NYHA standard, into class I group (n=10), class II group (n=21), class III group (n=33) and class IV group (n=28). All patients were again divided into diastolic heart failure group (n=29) and systolic heart failure group (n=63) according to left ventricular ejection fraction (LVEF). The healthy controls (n=50) with matched sex and age were chosen into control group. The scores of HFEI and level of plasma NT-proBNP were detected in all groups.Results ①HFEI and level of plasma NT-proBNP increased and LVEF decreased in CHF group compared with control group (P<0.05). As the increase of NYHA class, the scores of HFEI and level of plasma NT-proBNP increased gradually, and LVEF decreased gradually, and comparison among groups had statistical difference (P<0.05). ②The scores of HFEI and level of plasma NT-proBNP were higher in systolic heart failure group than that in diastolic heart failure group (P<0.05). ③The level of plasma NT-proBNP was positively correlated to HFEI (r=0.826,P<0.05), and negatively correlated to LVEF (r=-0.613,P<0.05).Conclusion The scores of HFEI and level of plasma NT-proBNP can further improve the diagnostic level of CHF in clinic, which can be taken as an important indicator for reviewing comprehensively heart function in CHF patients.
Keywords：Chronic heart failureHeart failure echocardiography indexN-terminal pro-brain natriuretic peptideHeart function
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 464-466 )