Relationship among tumor mass, heart function and pulmonary arterial hypertension (PAH) and postoperative pathological observation in patients with left atrial myxoma
WANG Quan-yi
ZHAO Yan-mei
ZHANG Qiu-lan
Abstract：Objective To investigate the relationship among tumor mass, heart function and pulmonary arterial hypertension (PAH) and postoperative pathological observation in patients with left atrial myxoma.Methods The data was retrospectively analyzed in the patients (n=57, male 38, female 19 and aged from 34 to 83) treated in the Affiliated Hospital of Jining Medical College from Jul. 2013 to Jul. 2016. All patients were divided, according to the grading of New York Heart Function Assessment (NYHA), into grade I group (n=9), grade II group (n=19), grade III group (n=22) and grade IV group (n=7). The levels of left ventricular ejection fraction (LVEF), left ventricular end-diastolic inner diameter (LVEDd) and PAH were detected, and cardiac myxoma was observed after HE staining in all patients before and after tumor surgery.Results The tumor mass of cardiac myxoma showed an ascending trend as grading of NYHA increased in the patients (allP<0.05). The level of LVEF showed a descending trend, and LVEDd and PAH showed an ascending trend as grading of NYHA increased in the patients in all groups before the surgery (allP<0.05). The level of LVEF increased and LVEDd and PAH decreased 3 m after the surgery in all groups (allP<0.05). The tumor mass of cardiac myxoma was negatively correlated to LVEF (r=-0.497,P<0.001) and positively correlated to LVEDD and PAH (r=0.553,r=0.572, allP<0.01) before the surgery. The pathological observation on tumor body showed that there were vascular and tumor cell invasion.Conclusion The tumor mass is closely related to heart function and PAH, and surgery can improve heart function and PAH in patients with left atrial myxoma.
Keywords：Left atriumCardiac myxomaHeart functionPulmonary arterial hypertension
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 427-429 )