Effect of periodontal treatment on level of serum C-reactive protein in patients with coronary heart disease complicated by chronic periodontitis: a Meta-analysis
LI Ben-lei
CHEN Zhuo-bin
FANG Dong
WANG Yang-gan
Abstract：Objective To review systematically the effect of domestic and overseas periodontal treatment on level of serum C-reactive protein (CRP) in patients with coronary heart disease (CHD) complicated by chronic periodontitis.Methods The databases of PubMed, Cochrane Library, EMbase, CNKI, VIP and WanFang Database were retrieved with computer from database establishing time to Nov. 2015 for collecting all literature about the effect of periodontal treatment on level of serum CRP in patients with CHD complicated by chronic periodontitis. The quality of the included studies was critically reviewed and data was extracted. The eligible literature was given a Meta-analysis.Results There were totally 10 studies included involving 920 patients. The results of Meta-analysis showed that periodontal treatment decreased significantly the level of serum CRP in patient group compared with control group (MD=-0.86, 95%CI: -1.33~ -0.39, P=0.0003).Conclusion The current studies indicate that periodontal treatment can not only improve periodontal condition, but also reduce significantly the level of inflammation in CHD patients, which is beneficial to the prevention and treatment of CHD.
Keywords：Coronary heart diseaseChronic periodontitisC-reactive proteinPeriodontal treatmentMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 397-402 )