Key point of clinical research protocol design -- the choice of reference drug
WENG Hong
YIN Qing-feng
WANG Chao-yang
ZENG Xian-tao
Abstract：The aim of clinical trials for drugs is to ensure the safety and effectiveness, and its ultimate goal is to improve the appropriateness of drug administration and patients' quality of life. Controlled group is frequently used in clinical studies, and the key is the choice of reference drug, which is never made easy. An optimal choice of reference drug through taking into consideration the research purpose and medical requirements will contribute to the value of clinical trials to medical practice. In this paper, we discuss the ways to choose appropriate control drugs, based on illustrative examples.
Keywords：Clinical researchClinical trialControlled studyReference drug
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 385-387 )