Effects of adiponectin levels on cardiac function and clinical outcome of patients with AMI after emergency PCI
LI Yun-wei
LI Yan-ming
HONG Yan
WAN Qi-lin
HE Rui-li
Abstract：Objective To investigate the effects of adiponectin levels on cardiac function and clinical outcome of patients with acute myocardial infarction (AMI) after emergency percutaneous coronary intervention (PCI).Methods 110 patients with AMI after emergency PCI were chosen from May 2012 to May 2015 in Huaihe hospital and divided into two groups: group A (76 patients with serum adiponectin <8.5 mg/L) and group B (34 patientswith serum adiponectin ≥8.5 mg/L). Laboratory-related indicators, echocardiographic parameters, coronary angiography, MACE incidence and mortality were compared between the two groups.Results There were no significant differences in the levels of Creatinine (Cr), Urea nitrogen (BUN), high-sensitivity C-reactive protein (hs-CRP), triglyceride (TG), total cholesterol (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C), apolipoprotein A (Apo-A) and apolipoprotein B (Apo-B) in the two groups (P>0.05). The fasting blood glucose level in group B was significantly lower than that in group A (P<0.05). There was no significant difference in left atrial diameter (LAD) and left ventricular end-diastolic diameter (LVEDd) levels between the two groups (P>0.05). The level of left ventricular ejection fraction (LVEF) in group B was significantly higher than that in group A (P<0.05). There was no significant difference in the number of arterial branches, obstruction vascular position and Thrombolysis In Myocardial Infarction (TIMI) grade of coronary artery between the two groups (P>0.05). The level of corrected TIMI frame count (CTFC) in group B was significantly lower than that in group A (P<0.05). There was no significant difference in mortality between the two groups (P>0.05). The incidence of MACE in group B was significantly lower than that in group A (P<0.05).Conclusion Higher adiponectin level on patients with AMI after emergency PCI can efficiently reduce the MACE occurrence risk and improve the cardiac function.
Keywords：AdiponectinAMIPCICardiac functionPrognosis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 331-334 )