Study on the relationship between serum uric acid, high sensitive C - reactive protein and risk stratification of acute coronary syndrome
LI Jie-wen
Abstract：Objective To explore the relationship between serum uric acid (SUA), high sensitive C-reactive protein (hs-CRP) and the different risk stratification of acute coronary syndrome (ACS).Methods 126 ACS patients in our Zhongshan People's Hospital from June 2012 to march 2014 were selected as observation group, including 36 patients with unstable angina pectoris (UA), 42 patients with non-ST-segment elevation myocardial infarction (NSTEMI), 48 patients with ST-segment elevation myocardial infarction (STEMI). At the same time, 52 non-ACS hospitalized patients were selected as the control group. The levels of SUA and hs-CRP were compared between the two groups, and the correlation between SUA and hs-CRP in patients with acute coronary syndromes was analyzed. Results The levels of SUA in patients with STEMI (735.19±146.98 mmol/L) and hs-CRP (17.06±7.87 mg/L) were significantly higher than those in NSTEMI group, UA group and control group (P<0.05). The levels of SUA in the NSTEMI group (579.13±60.12 mmol/L) and the UA group (470.37 ± 72.64 mmol/L) were significantly higher than those in the control group (349.09±80.74 mmol/L) (P<0.05). The levels of hs-CRP in the NSTEMI group (8.85 ±3.26 mg/L) were significantly higher than those in the control group (2.30±1.27 mg/L) (P<0.05), but were not different with the level of hs-CRP in the UA group (4.64±3.71 mg/L) (P>0.05). There was a significant positive correlation between SUA and hs-CRP levels (r=0.8766,P<0.01).Conclusion SUA and hs-CRP levels are closely related to ACS. Detection of SUA and hs-CRP levels are clinically significant for ACS stratification
Keywords：Acute Coronary SyndromeSerum uric acidHigh sensitive C-reactive protein
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 324-325,334 )