Association between erectile dysfunction and risk of coronary heart disease and all-cause mortality: a meta-analysis
LIU Tao
TIAN Guo-xiang
ZENG Xian-tao
WENG Hong
LIU Tong-zu
WANG Xing-huan
Abstract：Objective To evaluate the association between erectile dysfunction (ED) and risk of coronary heart disease (CHD) and all-cause mortality by meta-analysis.Methods The databases of PubMed, Embase, CNKI, Wanfang Data, CBM and VIP were retrieved for collecting cohort studies reported the association between ED and risk of CHD and all-cause mortality. Two authors independently screened literatures, extracted data and assessed the quality of included studies. Then meta-analysis was performed using Stata 14.0 software.Results A total of 11 cohort studies were included, in which seven reported the association between ED and risk of CHD and nine reported the association between ED and risk of all-cause mortality. The results of meta-analysis showed that ED was associated with increased risk of CHD (RR=1.54, 95%CI: 1.41~1.67,P<0.001) and all-cause mortality (RR=1.47, 95%CI: 1.18~1.84,P=0.001). No obvious publication bias was detected.Conclusion ED might increase the risk of CHD and all-cause mortality. Therefore, to cure ED patients might decrease the risk of CHD and all-cause mortality in clinical practice.
Keywords：Erectile dysfunctionCoronary heart diseaseAll-cause mortalityMeta-analysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 269-272 )