Relationship between pulse pressure index and Cys C, LVMI in elderly patients with essential hypertension
SUN Yao
YAO Jin-ya
GAO Hui
HE Di
Abstract：Objective To explore the relationship between the 24-hour ambulatory pulse pressure index with cystatin C (Cys C) and left ventricular mass index (LVMI) in elderly patients with essential hypertension.Methods The elderly hypertensive patients of Geriatrics Department of the Affiliated Hospital of North China University of Science & Technology from January, 2015 to January, 2016 were selected and given 24-hours ambulatory blood pressure monitoring to calculate the dynamic pulse pressure index (PPI) on the basis of 24-hour ambulatory blood pressure: PPI=24-hour dynamic pulse pressure/24-hour mean systolic blood pressure. Patients with PPI≤0.40 were enrolled as group A, patients with PPI 0.41-0.50 were enrolled as group B, patients with PPI≥0.51 were enrolled as group C. Cys C and LVMI were measured and calculated.Results Body Mass Index (BMI), total cholesterol (TC) and blood urea nitrogen (BUN) of the three groups had a tendency to increase, and HR has a downward trend, but the difference was not statistically significant (P>0.05). The Cys C and LVMI of the three groups showed an increasing trend, the difference was statistically significant (P<0.05). Cys C and LVMI were positively correlated with PPI (r=0.923, 0.890,P<0.05), and had no significant correlation with other indexes (P>0.05).Conclusion 24-hour ambulatory PPI was positively correlated with Cys C and LVMI in elderly hypertensive patients, and Cys C was more correlated with LVMI and 24-hour ambulatory PPI.
Keywords：Elderly essential hypertensionPulse pressure indexCystatin CLeft ventricular mass index
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 81-83 )