Evaluation of FFR combined with CAG on major adverse cardiac events in patients with coronary artery disease after PCI
YANG Lin
Abstract：Objective To evaluate coronary arteriography (CAG) combined with fractional flow reserve (FFR) on major adverse cardiac events (MACE) in patients with coronary artery disease (CHD) 12 months after received percutaneous coronary intervention (PCI).Methods From April 2014 to March 2015, 127 CHD patients in Taizhou Second People’s Hospital were enrolled. They were divided into 2 groups 12 months after received PCI: MACE group and Non-MACE group. Clinical data were recorded, including sex, age, smoking history, complications (hypertension, diabetes mellitus, hyperlipidemia), hospital discharge, CAG parameters (lesion site, vessel diameter and degree of stenosis) and FFR. Logistic regression analysis was performed to assess risk factors for MACE.Results There were 80 males (63.0%) and 47 females (37.0%). The average age was 64.8±9.5 years old. The average body mass index was 23.0±2.4 km/m2. 111 (87.4%) patients were classified in Ⅱ-Ⅲ grade of NYHA heart function classification and 16 patients were classified as IV grade (12.6%). 65 patients (51.2%) had history of diabetes mellitus, 71 patients (55.9%) had hypertension history, 89 patients (70.1%) had hyperlipidemia history and 74 patients (58.3%) had smoke history. The average stenosis degree of CAG was (96.1±4.0) %; the average FFR was 0.97±0.06. Result of univariate analysis showed that there was no significant difference between MACE group and non-MACE group in gender, age, body mass index, NYHA cardiac function grade, lesion site, vessel count, smoking history and hospital discharge (P>0.05). Result of logistic regression analysis showed that risk factors of MACE were FFR, hyperlipidemia and diabetes mellitus at 12 months after PCI (P<0.05).Conclusion The factors that affected MACE at 12 months after PCI were low levels of FFR, hyperlipidemia, and diabetes. The severity of coronary artery stenosis assessed by CAG alone did not predict MACE. It is suggested that FFR should be also detected.
Keywords：Fractional flow reserveCoronary arteriographyCoronary artery diseaseMajor adverse cardiac events
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1511-1514 )