Analysis of arrhythmia and hypertension in OSAHS patients with different severity

LI Li-li

doi:10.3969/j.issn.1674-4055.2016.12.23

Abstract：Objective To investigate the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and arrhythmia and hypertension.Methods 104 OSAHS patients in The General Hospital of Bureau of Mines from March 2014 to February 2016 were enrolled, including 63 males and 41 females, aged 38 to 67 years, mean age (51.91±9.78) years. Arrhythmia (paroxysmal supraventricular tachycardia, atrioventricular block, etc.) and the occurrence of hypertension in OSAHS patients with different severity were observed.Results Among the 104 OSAHS patients, there were 51 patients with mild OSAHS, including 30 males and 21 females with a mean age of (50.21±9.28) years; 21 patients with moderate OSAHS, including 13 males and 8 females with a mean age of (51.73±11.63) years old; 32 patients with severe OSAHS, including 20 males and 12 females with a mean age of (52.09±10.43) years. There were no significant differences in the age and sex of OSAHS patients (P>0.05). The systolic and diastolic blood pressure of severe OSAHS group were significantly higher than those of mild and moderate OSAHS group (P<0.05). The levels of systolic and diastolic blood pressure in moderate OSAHS group were significantly higher than those in mild OSAHS group (P<0.05). The incidence of hypertension and arrhythmia in OSAHS group was 46.88% and 46.88%, respectively, which was significantly higher than that in mild OSAHS patients (P<0.05). The proportion of hypertensive patients with arrhythmia in OSAHS group was 28.13%, which was significantly higher than that in other groups (P<0.05). The incidence of supraventricular tachycardia (SVT), sinus arrest (SA), Ⅱ atrioventricular block (AVB)and Ⅱ°Ⅱ AVB in severe OSAHS group were 15.63%, 12.50%, 25.00% and 14.29% respectively. The incidence of SVT, SA, Ⅱ°Ⅰ type AVB and Ⅱ°Ⅱ type AVB in moderate OSAHS group were 14.29%, 9.52%, 9.52% and 14.29%, respectively. In mild OSAHS group, only 2.29% of patients developedⅡ°Ⅰ type AVB.Conclusion Different degrees of OSAHS patients with arrhythmia and the incidence of hypertension is different, in which severe SAHS patients with arrhythmia and high incidence of hypertension should be given high priority.