Risk factors of no-reflow during primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction
YUAN Chi
KE Yong-sheng
KE Ke
Abstract：Objective To analyze the relevant risk factors of no-reflow during primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI).Methods STEMI patients undergone primary PCI were chosen (n=166, male 139, female 27, aged from 36 to 91 and average age=63.10±11.96) from the Department of Cardiovascular Diseases of the First Affiliated Yijishan Hospital of Wannan Medical College from May 2012 to Dec. 2015. All patients were divided into normal perfusion group (n=142) and no-reflow group (n=24) according to the outcomes of angiography after vascular mechanical patency. The general clinical materials including ischemia time and complicating basic diseases were collected. The samples of vein blood were collected at the time of hospitalization and after hospital admission for detecting neutrophil percentage, platelet count (PLT) and low-density lipoprotein-cholesterol (LDL-C), and diseased vascular diameter and target lesion length were measured.Results The ischemia time and neutrophil percentage were all higher in no-reflow group than those in normal perfusion group (allP<0.01). The results of regression analysis showed that ischemia time>6 h (OR=1.578, 95%CI: 1.245~2.000) and neutrophil percentage>80.0% (OR=3.405, 95%CI:1.027~11.293) were risk factors of no-reflow after primary PCI.Conclusion In the patients with acute STEMI undergone primary PCI, ischemia time is longer and neutrophil percentage increases significantly and probability of no-reflow will be higher.
Keywords：Acute ST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionNo-reflow
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1354-1356 )