Correlation between slope, intercept and dynamic changes in ventricular repolarization during QT-RR interval regression equation
LIU Ying-jie
QIN Di-mao
Abstract：Objective Value of slope and intercept for dynamic changes in ventricular repolarization during QT-RR interval regression equation in healthy people, people with torsade de pointes (TDP) or idiopathic ventricular fibrillation (IVF).Methods This study included 466 healthy subjects and 17 patients with torsade de pointes VT, 10 patients with IVF and 7 patients with TDP received 24-hour dynamic electrocardiogram in the Chengdu Third People’s Hospital from January 2014 to December 2015. The QT-RR interval linear regression equation [QT] = A [RR] + B (A is the slope, B is the intercept) is calculated by linear regression analysis of each dynamic ECG data by QT interval automatic analysis system.Result In the QT-RR interval linear regression equation of healthy subjects, the slope of female was significantly greater than that of male (0.185±0.036vs. 0.161±0.033,P<0.001), and the intercept was significantly less than that of male (0.229±0.028vs. 0.240±0.027,P<0.001). In the linear regression equation of all healthy subjects, the scatter plot of slope and intercept showed a significant negative correlation (B=-0.62A+0.34,r=-0.79). The scatter plot showed that the scatter plot of IVF patients was located in the upper left corner of the scatter gram of healthy subjects compared with healthy subjects, and the scatter plot of TDP patients was located above the healthy subjects.Conclusion In 24-hour ambulatory ECG monitoring, QT-RR interval linear regression equation slope and intercept indicators, can more effectively predict abnormal ventricular repolarization dynamic changes.
Keywords：Dynamic changes in ventricular repolarization24-hour dynamic electrocardiogramLinear regression analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1237-1240 )