Effect of PCI on regional and global left ventricular systolic function in patients with coronary artery disease

JIN Hai-bin

doi:10.3969/j.issn.1674-4055.2016.09.20

Abstract：Objective To evaluate the effect of percutaneous coronary intervention (PCI) on regional and global left ventricular systolic function in patients with coronary artery disease (CHD).Methods 30 CHD patients underwent PCI were enrolled as study group, and 30 healthy volunteers were enrolled as control group. All groups received three-dimensional echocardiography (RT-3DE) inspection before and after PCI. We measured and compared change of global and regional left ventricular end-diastolic volume (EDV), left ventricular end-systolic volume (ESV) and left ventricular ejection fraction (LVEF).Results Preoperative EDV and ESV of study group were significantly higher (P<0.05) and LVEF was significantly lower than those of control group (P<0.05). Postoperative EDV and ESV were significantly reduced, and EF was significantly increased after one month (allP<0.05) in study group. Postoperative EDV, ESV and LVEF of study group after one month were not different with control group (P>0.05). After PCI, the partial end diastolic volume (rEDV) and partial end-systolic volume (rESV) values of apical cap, apical segment before the interval, the interval before the basal segment, the middle section before the interval, anterior apical segment, anterior basal segment, the middle section of the front wall were significantly reduced, the partial ejection fraction (rEF) values were significantly increased, the difference was statistically significant (allP<0.05).Conclusion After PCI intervention, the regional and global left ventricular systolic function in CHD patients are significant improved. RT-3DE can be used to quantitatively evaluate left ventricular systolic function of patients.