Effects on growth differentiation factor 15 and hs-CRP in patients with aged type 2 diabetics with coronary heart disease by different treatment
LI Dao-hong
XU Xiao
YANG Xu-feng
Abstract：Objective To investigate effects on growth differentiation factor 15 and hs-CRP in patients with aged type 2 diabetics with coronary heart disease by different treatment.Methods A total of 70 patients with coronary heart disease complicated with type 2 diabetes were selected from January 2014 to June 2015 in The First People's Hospital of Wujiang in Suzhou. The patients were randomly divided into two groups; each group has 35 patients. Patients of control group were given atorvastatin combined with aspirin, patients of observation group were received glargine insulin on the basis of treatment of control group. Blood sugar control, level of growth differentiation factor 15 and hs-CRP were measured.Results After treatment, level of fasting blood-glucose [(8.56 ±1.20) mmol/L], 2-hour postprandial blood glucose [(8.97±1.01) mmol/L] and glycosylated hemoglobin [(7.01± 1.02) %] of observation group were decreased, and were better than control group (P<0.05). In control group, level of fasting blood-glucose was (9.93±1.50) mmol/L, level of 2-hour postprandial blood glucose was (9.01±1.50) mmol/L and level of glycosylated hemoglobin was (9.87±1.54) % after treatment. Level of growth differentiation factor 15 and hs-CRP were both decreased in two groups (P<0.05) after treatment.Conclusion Atorvastatin Combined with insulin glargine can effectively control blood sugar and improve expression of growth differentiation factor 15 and hs-CRP in patients with aged type 2 diabetics with coronary heart disease compared to traditional treatment.
Keywords：AtorvastatinInsulin GlargineCoronary Heart Disease Complicated with Type 2 Diabetes Mellitus
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1053-1055 )