Effect of Tianmagouteng decoction on heart function and cardiovascular events in H hypertensive patients with left ventricular hypertrophy
WANG Yan-hui
LIU Yan-jun
Abstract：Objective To explore the effect of Tianmagouteng decoction on heart function and cardiovascular events (nonfatal myocardial infarction, stroke, and cardiovascular death) in H hypertensive patients with left ventricular hypertrophy.Methods A retrospective analysis of 126 H type hypertension patients from January 2014 to May 2015 in Chinese Medicine Hospital of Qinhuangdao City was conducted. The patients were divided into control group and observation group with 63 patients in each group. the control group received enalapril maleate-folate tablets, the observation group received Tianmagouteng decoction on the basis of treatment of control group. The levels of plasma homocysteine (Hcy), left ventricular ejection fraction (LVEF), the ratio of E peak and A peak (E/A), and the incidence of major cardiovascular events were recorded and compared between the two groups. Results The levels of Hcy in the two groups were both significantly decreased after treatmnet (P<0.05). After the treatment, the E/A and LVEF of the two groups were both significantly improved (P<0.05). The E/A and LVEF of the observation group were significantly higher than that of the control group (P<0.05). The incidence of major cardiovascular events in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Tianmagouteng Decoction can significantly reduce the Hcy of H hypertensive patients with left ventricular hypertrophy, improve diastolic and systolic function and lower the occurrence of major cardiovascular events, which has a high clinical value.
Keywords：Tianmagouteng DecoctionH-type hypertensionLeft ventricular hypertrophyCardiac functionCardiovascular events
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 997-998 )