Analysis on cases of nosocomial infection in the department of cardiovascular surgery of a grade III-A hospital in five consecutive years
DAI Li-wen
DING Jing-mei
FU Ju-fang
LIU Bing
SUN Hui-ying
SHI Jie-ran
Abstract：Objective To survey the status of nosocomial infection in the department of cardiovascular surgery of a grade III-A hospital in five consecutive years and analyze relevant factors for taking effective measures to reduce the incidence of nosocomial infection.Methods The discharged patients (n=19 025) were chosen from the department of cardiovascular surgery of a grade III-A hospital from Jan. 2010 to Dec. 2014, and among them 553 were diagnosed as nosocomial infection cases. The general materials and relevant data were collected from 553 patients including sex, age, hospitalization status, surgery status and duration of staying in intensive care unit (ICU) by applying retrospective analysis method.Results In five consecutive years, there were totally 553 patients with nosocomial infection, among them 343 (62%) were the male, 210 (38%) were the female, their age was from 1.0 to 52, and there were 77 (13.9%) patients aged over 60. There were 119 (21.5%) patients undergone rescue, 467 (84.4%) accepted surgery, 447 (80.8%) with blood transfusion, and 57 (10.3%) with dialysis. The duration of staying in ICU was 4.0 (2.0-9.0) d, and there were 276 (49.9%) patients with duration of staying in ICU≥5 d. The average highest body temperature was (38.85±0.68) ℃ in patients during staying in hospital, and among them there were 248 (44.8%) cases with the highest body temperature≥39.0℃. There were 309 (55.9%) patients treated with the third generation cephalosporin before the surgery, and there were 2.0 (1.0-3.0) kinds of antibiotics used after the surgery. The indwelling duration of venous catheter was 7.0 (5.0-8.5) d and there were 284 (51.4%) patients with indwelling duration≥7 d. There 314 (56.8%) patients with albumin<40 g/L and 272 (49.2%) patient with hematocrit (Hct)<0.40. The most common nosocomial infection types were pulmonary infection (43.6%), upper respiratory tract infection (30.0%) and bloodstream infection (25.7%). The results of binary Logistic regression analysis showed that female and the third generation cephalosporin before the surgery were protective factors of bloodstream infection, and age≥60, duration of staying in ICU≥5 d, the highest body temperature≥39.0 ℃, albumin<40 g/L, hematocrit (Hct)<0.40 and indwelling duration of venous catheter≥7 d were risk factors.Congenital heart disease and blood transfusion were protective factors of pulmonary infection, and duration of staying in ICU≥5 d, dialysis, surgery, indwelling duration of venous catheter≥7 d, and kinds of antibiotics≥3 were risk factors.Conclusion There were a lot of factors related to nosocomial infection, and the measures of improving physical functions, decreasing duration of staying in ICU, reducing of indwelling duration of venous catheter and reasonably administrating of antibiotics should be taken for reducing the incidence of nosocomial infection.
Keywords：Nosocomial infectionInfection siteRisk factorsDepartment of cardiovascular surgery
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 952-954 )