Correlation analysis between QRS duration with plasma brain natriuretic peptide and left ventricular ejection fraction in patients with chronic heart failure
QI Jian-wei
LI Xiao-hui
YAN Wen-jie
LU Mei-chao
LI Cheng-fang
Abstract：Objective To investigate the correlation of QRS duration with plasma brain natriuretic peptide (BNP) and left ventricular ejection fraction (LVEF) in patients with chronic heart failure (CHF).Methods 200 CHF patients in Pingshan County People's Hospital from January 2012 to December 2014 were selected as observation group, 60 healthy persons were selected as control group. All participants were taken ECG examination, and the widest V5 lead QRS duration was measured. The QRS duration, plasma BNP and LVEF were compared between two groups, and the correlation was analyzed.Results The QRS duration and level of plasma BNP in observation group was significantly higher than control group (P<0.01). LVEF in observation group was significantly lower than control group (P<0.01). 112 patients had shorter QRS duration (≤120 ms), and 98 patients had longer QRS duration (>120 ms). Level of plasma BNP in patients with shorter QRS duration were significantly lower than patients with longer QRS duration (P<0.01). LVEF in patients with shorter QRS duration was significantly higher than patients with longer QRS duration (P<0.01). Result of pearson correlation analysis showed that QRS duration and of observation group was significantly positively correlated with plasma BNP (r=0.815,P<0.01), but significantly negatively correlated with LVEF (r=-0.723,P<0.01).Conclusion The QRS duration of CHF patients is significantly increased, and significantly correlated with plasma BNP and LVEF, which can be used as an important auxiliary indicator for cardiac function in patients with CHF.
Keywords：Chronic heart failureQRS durationBrain natriuretic peptideLeft ventricular ejection fraction
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 935-937 )