Regulation effect of Zhibitai capsule on lipid metabolism disorder in patients with type 2 diabetes
HE Chang-neng
WANG JIA-lin
Abstract：Objective To investigate Regulation effect of Zhibitai capsule on lipid metabolism in patients with type 2 diabetes.Methods 90 type 2 diabetes patients with lipid metabolism disorder from The First People's Hospital of Hefei in 2011.3-2012.3 were randomly divided into control group (45 cases) and study group (45 cases). The control group received simvastatin. The study group received Zhibitai capsule. All were treated for 6 weeks. Total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) were compared before and after treatment. Clinical symptoms and adverse events were observed.Results TC and LDL-C were decreased and HDL-C was increased significantly in both study group and control group after treatment (P<0.05), but were not different between these two groups (P>0.05). TG of study group was much lower than control group after treatment [(0.57±0.18) mmol/Lvs. (0.37±0.06) mmol/L,P<0.05]. Rate of adverse events was obvious lower than control group (0%vs. 11.1%,P<0.05). More patients of study group had improvement of symptoms than control group, including chest distress, abdominal distension and shortness of breath (P<0.05). Conclusion Zhibitai capsule is more effective and safe for lipid metabolism disorder in type 2 diabetes mellitus patients, and is worth popularizing in clinic.
Keywords：Zhibitai capsuleSimvastatinType 2 diabetesLipid metabolism
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 827-829 )