Remote ischemic preconditioning provides cardio protection in patients recieved coronary stent implantation
LUO Sheng-jie
ZHOU Yu-jie
JIA De-an
GE Hai-long
YANG Shi-wei
Abstract：Objective This study assessed the protective effect of remote ischemic preconditioning (RIPC) in patients undergoing stent implantation.Methods 148 participants undergoing coronary stent implantation with normal baseline troponin values were analyzed. Subjects were randomized to two groups: RIPC group (n=75) received RIPC 2 hours before procedure of percutaneous coronary intervention (PCI), and control group (n=73). The primary outcomes were high sensitive cardiac troponin I (hscTnI) level and incidence of myocardial infarction (MI 4a, defined as hscTnI >0.20 ng/mL) at 16 hours after PCI procedure.Results The median hscTnI at 16 hours after PCI was lower in the RIPC group compared with control group (0.11 versus 0.27ng/mL;P<0.05). Incidence of MI 4a was fewer in RIPC group compared with the control group (39%vs. 56%,P<0.05).Conclusion Remote ischemic preconditioning can reduce post-PCI troponin I release and incidence of MI 4a in non-diabetic patients undergoing coronary stent implantation.
Keywords：Remote ischemic preconditioningPercutaneous coronary interventionCoronary artery heart diseaseStentsTroponin
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 808-811 )