Clinical efficacy of radiofrequency catheter ablation in patients with atrial fibrillation

HU Qiang; HAN Su-xia; LI Peng

doi:10.3969/j.issn.1674-4055.2016.06.17

Abstract：Objective To investigate the clinical efficacy of radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF).Methods AF patients (n=100, male 52, female 48, aged from 18 to 70 and average age=54.28±8.31) undergone RFCA treatment were chosen from Apr. 2010 to Jun. 2015. The indexes of left atrial diameter (LAD), left ventricular end-diastolic inner diameter (LVEDd), left ventricular end-systolic diameter (LVESd), left ventricular ejection fraction (LVEF), ratio of left ventricular peak early diastolic mitral flow velocity (E) to late diastole mitral flow velocity (A, E/A), curative effect and incidence of complications were compared before and after treatment.Results The percentage of male patients was 52% and average age was (54.28±8.31). The percentage of patients with paroxysmal AF was 62% and AF course was (16.4±6.5) m. The percentage of patients with hypertension was 33%, diabetes, 9%, coronary heart disease, 22%, and mitral inadequacy, 36%. The percentage of patients with NYHA grade I was 39%, NYHA grade II, 45%, and NYHA grade III, 16%. LAD was significantly lower after treatment (45.19±7.86) mm than that before treatment (55.78±11.39) mm (P<0.05). LVEF had no significant difference before and after the treatment (P>0.05). LVEDd was significantly lower after treatment (44.13±4.01) mm than that before treatment (50.62±5.42) mm (P<0.05). LVESd was significantly lower after treatment (27.01±3.71) mm than that before treatment (32.11±5.30) mm (P<0.05). E/A increased after the treatment (P<0.05). The total success rate was 86.00% (86/100) after treatment for 1 y, and success rate for paroxysmal AF was 93.51% (58/62) and for sustained AF, 68.42% (26/38). The total recurrent rate was 14.00% (14/100), and recurrent rate for paroxysmal AF was 6.45% (4/62) and for sustained AF, 31.58% (12/38). The success rate was significantly higher, and recurrent rate was significantly lower for paroxysmal AF than that for sustained AF (P<0.05). The complications occurred in 9 patients during or after treatment, among them 7 with paroxysmal AF and 2 with sustained AF.Conclusion RFCA is safe and effective based on small-sampled study, but recurrent rate is still observed. The patients with paroxysmal AF should accept RFCA treatment as soon as possible.