Application of multivariate Meta-analytical model in Meta-analysis of repeated measures outcomes
MENG Xiang-yu
TIAN Guo-xiang
ZHOU Xin-yu
SUN Zhu
LI Sheng
ZENG Xian-tao
Abstract：Repeated measures data are one of major data types in medical studies, especially in those related to prognosis. Correlation exists among multiple measures values corresponding to different time points, thus separate analyses for single outcome in secondary studies, e.g. Meta-analysis, should be avoided since bias might be introduced and the multivariate Meta-analysis model which well manages dependence across effect sizes is recommended. In this article, a multivariate Meta-analytical model was presented to merge multiple binary repeated measures outcomes, as well as actualized in R software through example analysis.
Keywords：Multivariate Meta-analytical modelRepeated measures outcomesMeta-analysisPrognosis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 647-651 )