Correlation between blood pressure load and circadian rhythm in elderly hypertension patients with target organ damage
He Xing-qiu
PAN Miao-jun
XIE Zhi-ling
Abstract：Objective To investigate the correlation between blood pressure load and circadian rhythm in elderly hypertension patients with target organ damage.Method 150 elderly patients with primary hypertension of Guangdong Reclamation Central Hospital between 60 and 80 years old were included from January 2012 to December 2014.Patients were divided into target organ damage group and simple hypertensive group according to whether or not having target organ damage, with 24-hour ambulatory blood pressure monitoring. Characteristics of blood pressure load and circadian rhythm in two groups, and relevant factors of target organ damage in elderly hypertension patients were analyzed.Results Blood pressure load of target organ damage group was significantly higher than simple hypertension group(52.32±11.89)%, especially at night(63.31 ±13.26)% (P<0.05).The circadian rhythm of target organ damage group was significantly higher than simple hypertension group (P<0.05). Nighttime blood pressure, average systolic blood pressure in 24 hours, blood lipids, carotid artery intima-media thickness, left ventricular mass index, 24-h urinary albumin, and cardiovascular disease were relative with target organ damage in elderly hypertensive patients (P<0.05).Conclusion The elderly hypertensive patients should pay attention to correct disorders of circadian rhythm and pay attention to nighttime blood pressure load in order to minimize damage to the target organ.
Keywords：ElderlyHypertensionCircadian rhythmBlood pressure loadTarget organ damage
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 468-470 )