Three-dimensional speckle tracking imaging for reviewing myocardial strain parameter changes in patients with different severity coronary artery stenosis

LI Dan; LIU Mei; NIU Hai-yan; DUAN Ya-qi; HUANG Xiao-ling; WANG Jian-hua

doi:10.3969/j.issn.1674-4055.2016.04.11

Abstract：Objective To review the global myocardial strain by applying three-dimensional speckle tracking imaging (3D-STI) in patients with different severity coronary artery stenosis.Methods The patients with suspected coronary heart disease (CHD,n=63) were chosen from Dec. 2013 to May. 2014. According to the outcomes of coronary angiography (CAG), the patients were divided into control group (without coronary artery stenosis,n=10), mild stenosis group (mild group, stenosis rate ≤50%,n=9), moderate stenosis group (moderate group, 50%<at least 1-vessel stenosis≤75%,n=10) and severe stenosis group (severe group, at least 1-vessel stenosis>75%,n=34). The global myocardial strain parameters were obtained by applying 3D-STI, including global long axis strain (GLS), global radial strain (GRS), global circumferential strain (GCS) and global area strain (GAS) of left ventricular systolic peak. The difference in global myocardial strain parameters of different severity coronary artery stenosis was compared.Results All myocardial strain parameters decreased significantly in severe group compared with other groups. GLS, GRS and GAS decreased significantly in moderate group compared with control group, and GAS decreased significantly in moderate group compared with mild group. GAS decreased significantly in mild group compared with control group (P<0.05).Conclusion 3D-STI can be taken as an effective detective method for reviewing global left ventricular systolic function in CHD patients without ventricular wall motion. GAS is a parameter with the highest sensitivity and repeatability. As the increase of coronary artery stenosis severity, the damage of myocardial strain will become heavier and GAS damage is the most significant.