Clinical efficacy of atorvastatin combining trimetazidine on coronary heart disease
LIU Yong-dong
GAO Kang
Abstract：Objective To discuss the clinical efficacy of atorvastatin combining trimetazidine on coronary heart disease (CHD).Methods CHD patients (n=140) were chosen from May 2013 to Nov. 2014, and randomly divided into control group and treatment group (eachn=70). The control group was treated with routine therapy and trimetazidine, and treatment group was additionally given atorvastatin. The clinical efficacy, angina attack and duration and adverse reactions were compared between 2 groups.Results The total effective rate was 97.1% in treatment group and 82.8% in control group (P<0.05). The levels of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein-cholesterol (LDL-C) was significantly lower, and level of high-density lipoprotein-cholesterol (HDL-C) was significantly higher in 2 groups after treatment (P<0.05), which was more significant in treatment group (P<0.05). The number of angina attack in a week and duration of every angina attack were significantly less in treatment group than those in control group (P<0.05).Conclusion Atorvastatin combining trimetazidine is safe and effective in treatment of CHD angina, which can significantly relieve the symptoms of angina and improve blood fat status in CHD patients.
Keywords：Atorvastatintrimetazidinecoronary heart disease (CHD)
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 370-371,376 )