Literature analysis on adverse reactions of antiarrhythic drugs
WANG Yu-hong
SUN Ming
ZHANG Yu-zhen
MA Nan
FENG Mu-dan
Abstract：Objective To study the characteristics and laws of adverse reactions (ADR) of antiarrhythic drugs, and provide the reference for selection of drugs and determination of ADR in clinic.Methods The cases of ADR of antiarrhythic drugs (n=326) reported from 1995 to 2015 were counted and analyzed.Results Among 326 ADR cases, there were 187 (57.4%) male cases and 139 (42.6%) female cases. In the aspect of drug classification, there were 115 cases (35.3%) of ADR induced by type I antiarrhythic drugs, which had the highest ratio. There were 108 cases (33.1%) of ADR induced by amiodarone, and it was a single drug induced the most cases of ADR. There were totally 155 (47.5%) cases of severe ADR.Conclusion The administration of antiarrhythic drugs should be paid more attention to and drugs information should be mastered for reducing ADR.
Keywords：Antiarrhythic drugsAdverse drug reactionsAmiodaroneSodium channel inhibitor
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 355-357 )