Multiple-factors Logistic regression analysis of in-stent restenosis after percutaneous coronary intervention
LIU Zheng
YU Wei-guo
ZHANG Lei
CHEN Jin-liang
LI Hai-jun
ZHANG Fu-li
GAO Yi-sen
Abstract：Objective To analyze the risk factors of in-stent restenosis after percutaneous coronary intervention (PCI), and provide the theoretical evidence for preventing in-stent restenosis.Methods The data of patients with suspected coronary restenosis (n=126, male 87, female 39 and average age=57.2±9.8) was analyzed retrospectively from Mar. 2010 to Jan. 2015. All patients were divided into restenosis group (n=36) and control group (n=90) according to outcomes of coronary angiography (CAG). The Gensini integrals were calculated, and indexes of LDL-C, HDL-C, TC, TG, fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) were detected in 2 groups after CAG.Results Compared with control group, the percentage of male and smoking patients, and those with hypertension and diabetes, coronary Gensini integrals, TC, TG, LDL-C, stent length and stent number increased, and level of HDL-C and stent diameter decreased in restenosis group (allP<0.05). Diabetes (OR=7.130, 95%CI: 1.680~12.754), smoking after PCI (OR=2.419, 95%CI: 1.013~6.215), coronary Gensini integrals (OR=10.537, 95%CI: 3.678~18.845), stent length (OR=1.593, 95%CI: 1.072~2.393) and stent number (OR=2.541, 95%CI: 1.169~3.745) were independent risk factors of in-stent restenosis after PCI. The stent diameter (OR=0.659, 95%CI: 0.485~0.873) was a protective factor of in-stent restenosis after PCI.Conclusion Diabetes, smoking, coronary Gensini integrals, stent length and stent number are independent risk factors of in-stent restenosis after PCI, and longer stent diameter is a protective factor.
Keywords：Coronary arteryIn-stent restenosisCoronary angiographyRisk factors
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 317-319 )