Echocardiogram for reviewing cardiac morphology and heart function in third trimester of pregnancy in patients with gestational hypertension diseases

LIU Xiao-yan; YANG Lei

doi:10.3969/j.issn.1674-4055.2016.03.16

Abstract：Objective To observe the changes of cardiac morphology and heart function in third trimester of pregnancy in patients with gestational hypertension diseases.Methods The patients (n=60) were chosen from Mar. 2012 to Apr. 2015, and divided into 3 groups: gestational hypertension group (group A,n=21), mild preeclampsia (group B,n=19) and severe preeclampsia (group C,n=20). Other 30 cases of normal pregnancy were selected as normal group. The indexes of cardiac morphology and heart function were collected by using color Doppler ultrasonic diagnostic apparatus.Results The percentage of cases of left ventricular abnormal geometry was 22.7%in group A, 27.3% in group B and 50.0% in group C (P>0.05). Compared with normal group, IVSTd, LVPWTd, LVDd, LAD, LVMI and RWT increased significantly in other 3 groups (P<0.05). Compared with group A, IVSTd, LVPWTd, LVDd, LAD and LVMI increased significantly in group C (P<0.05). Compared with group B, LVDd increased significantly in group C (P<0.05). RWT had no difference among group A, group B and group C (P>0.05). Compared with group A, IVSTd, LVPWTd, LVDd, LAD and LVMI had an ascending trend in group B but the difference was no significant (P>0.05). Compared with normal group, peak A increased (P<0.05), and E/A and RFF decreased (P<0.05) in other 3 groups. Compared with group A, peak A increased significantly (P<0.05), and peak E, E/A and RFF decreased significantly (P<0.05) in group C. There was no difference in CO, CI and LVEF between normal group and other 3 groups (P>0.05).Conclusion In patients with gestational hypertension diseases, the left ventricular wall thickness increases and left ventricular diastolic function is abnormal, which are more significant in patients with severe preeclampsia.