Influence of diabetes on different revascularizations in patients with unprotected left main coronary artery disease
WU Chang-yan
YU Xian-peng
CHEN Fang
LV Shu-zheng
YUAN Fei
Abstract：Objective To discuss the influence of diabetes on percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in treatment of unprotected left main coronary artery (LMCA) disease. Methods The data of patients with coronary heart disease (CHD) was analyzed retrospectively from Jan. 2003 to Jul. 2007, and the patients (n=922) were divided into PCI group (n=465) and CABG group (n=457) according to therapies. The incidence of adverse events, including death, myocardial infarction and re-revascularization, were compared between 2 groups and diabetic group and non-diabetic group respectively.Results The follow-up median was 7.1 y. After adjusting with multiple factors, PCI group and CABG group, whether or not patients with diabetes, had no statistical difference in mortality (P=0.41 in diabetic group,P=0.25 in non-diabetic group), and in risks of death, myocardial infarction and stroke (HR=0.79,P=0.40 in diabetic group,HR=0.82,P=0.35 in non-diabetic group). The incidence of re-revascularization was significantly higher in PCI group than that in CABG group (HR=2.11,P=0.02 in diabetic group,HR=2.37,P<0.001 in non-diabetic group). The risk of stroke was significantly higher in CABG group than that in PCI group (HR=0.23,P=0.02 in diabetic group,HR=0.40,P=0.02 in non-diabetic group).Conclusion Diabetes is not an independent influencing factor on revascularization strategies selection in treatment of unprotected LMCA disease.
Keywords：Unprotected left main coronary artery diseaseDiabetesCoronary artery bypass graftingPercutaneous coronary intervention
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 283-286 )