Comparisons of index of microcirculatory resistance and heart function of good and bad coronary collateral circulation in ST segment elevation myocardial infarction
WANG Shi-chao
Zhang Chun-quan
LIU Yu-hao
WU Yu
Shao Yi-bing
Xu Wen-liang
Wang Xu
Abstract：Objectives Comparisons of index of microcirculatory resistance and heart function of good and bad coronary collateral circulation in ST elevation myocardial infarction.Methods In Qingdao Municipal Hospital, 34 inpatients with ST segment elevation myocardial infarction (STEMI) from January 2012 to March 2014 were selected. These patients missed blood supply reconstruction (>12h), and then were performed coronary angiography and PCI after 15 days. The patients including 28 males and 6 females, from 31 to 82 years old (63.0±12.4 years old). According to the Rentrop grade, these patients were divided into 2 groups: collateral circulation formation group (group A, Rentrop=2-3,n=19) and collateral circulation formation adverse group (group B, Rentrop=0-1,n=15). The index of microcirculatory resistance (IMR) was measured after all patients underwent coronary angiography and stent implantation. Left ventricular end diastolic diameter (LVEDD) and left ventricular ejection fraction (LVEF) were measured before and in 3 months after procedure.Results No statistically significant difference was shown in age, gender, hypertension, diabetes mellitus and chronic myocardial infarction in two groups (P>0.05). Compared with B group, IMR [ (32 + 7.6)vs. (21.2 + 4.5)] was significantly decreased in A group (P<0.01). The LVEF of A group was significantly increased after procedure (P<0.05). LVEDD in B group was significantly increased after 3 months (P<0.05). Compared with A group, LVEDD was significantly increased [(47.4 + 2.4 mmvs. (53.6 + 5.0) mm], and LVEF was significantly decreased [(56.5 + 3.3) %vs. (46.1 + 8.8) %] in B group after PCI (P<0.05). The coronary collateral grading in all patients was negatively correlated with IMR (r=-0.601,P<0.001); IMR was positively correlated with LVEDD in 3 months after PCI (r=0.842,P<0.01); and IMR was negatively correlated with LVEF in 3 months after PCI (r=-0.830,P<0.01).Conclusion STEMI patients in poor coronary collateral circulation are more prone to microcirculatory dysfunction and worse heart function after PCI.
Keywords：Index of microcirculatory resistance (IMR)Collateral circulationPCICardiac function
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 183-185 )