Relationship between glycated hemoglobin and contrast-induced nephropathy after selective percutaneous coronary intervention in patients with unstable angina pectoris
WANG Su
YIN CHENG-qian
LI Zhao
WANG Qian
Abstract：Objective To discuss the relationship between glycated hemoglobin (HbAlc) and contrast-induced nephropathy (CIN) after selective percutaneous coronary intervention (PCI) in patients with unstable angina pectoris (UAP).Methods UAP patients treated with selected PCI (n=420) were chosen from Jan. 2015 and Oct. 2015, and the divided, according to the level of HbAlc, into test group (HbA1c≥6.5%,n=118) and control group (HbA1c<6.5%,n=302). The levels of creatinine (Cr) and endogenous creatinine clearance rate (CCr), and incidence of CIN were compared between 2 groups before and 36 h after PCI. The relationship between HbA1c level and CIN after PCI was analyzed.Results The incidence of CIN was 24.4% in test group and 0.67% in control group (P<0.05). The results of binary Logistic analysis showed that HbA1c level≥6.5% is the independent risk factor in UAP patients after selected PCI (OR=5.711; 95%CI: 2.475-13.785,P=0.000).Conclusion The incidence of CIN increases significantly in UPA patients with HbA1c level≥6.5% after selected PCI.
Keywords：Glycated hemoglobinContrast-induced nephropathyUnstable angina pectorisPercutaneous coronary intervention
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 66-68 )