Distinction of coronary atherosclerotic plaques with magnetic resonance imaging: a Meta-analysis
WANG Yong-zhi
LI Yun-juan
PU Kui
GUO Feng
ZHANG Hui
MI Chun-jing
Abstract：Objective To review the feasibility and veracity of magnetic resonance imaging (MRI) in distinction of coronary atherosclerotic plaques by using Meta-analysis method.Methods The databases of Cochrane Library, PubMed, OVID, EBSCO, CNKI, CBM and WanFang Database were retrieved with computer until to Dec. 31, 2014 for collecting studies on distinction of coronary atherosclerotic plaques with MRI, and screening the documents according to the recommendation by Cochrane Collaboration. The documents were analyzed by using STATA 12.0 software and Meta-disc 1.4 software, including heterogeneity test, public bias test, Meta-regression, clinical pragmatic investigation, pooled sensitivity (SEN), specificity (SPE), diagnostic odds ratio (DOR) and 95% confidence interval (95%CI). The summary receiver operating characteristic curve (SROC) and area under curve (AUC) were drawn and calculated. Results There were totally 6 documents included. SEN was [0.92 (95%CI: 0.86~0.9), SPE was [0.89 (95%CI:0.82~0.94)], DOR was [56.09 (95%CI: 18.41~212.49)], and AUC was 0.9451 in summarized identification of lipid-rich composition. SEN was [0.88 (0.79~0.94)], SPE was [0.96 (0.91~0.98)], DOR was [78.95 (22.01~283.28)], and AUC was 0.9291 in identification of calcification composition.Conclusion MRI is highly accurate in distinction of lipid-rich composition and calcification composition in coronary atherosclerotic plaques.
Keywords：Coronary arteryAtherosclerosisMagnetic resonance imagingMeta-analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 12-16 )