Clinical and prognosis analysis on cardiac resynchronization therapy
GUO Jian-ping
WANG Yu-tang
SHAN Zhao-liang
SHI Xiang-min
YUAN Hong-tao
LIN Kun
LI Jian
Abstract：Objective To analyze retrospectively the clinical materials and prognosis in patients with heart failure (HF) undergone cardiac resynchronization therapy (CRT). Methods The baseline and long-term follow-up materials were collected from HF patients with implantation of CRT-P/D (pacing/defibrillation) from 2001 to 2013. All patients were divided, according to the left ventricular function and remodeling indexes, into non-response group, response group and super-response group. The difference in clinical materials and outcomes was analyzed in 3 groups. Results There were 92 cases followed up for a long time after CRT, and 28 in non-response group, 37 in response group and 27 in super-response group. The percentage of patients with atrial fibrillation (AF) was 57.1%in non-response group, which was significantly higher than that in response group and super-response group (P=0.004). The indexes of left ventricular ejection fraction (LVEF), left ventricular end-diastolic inner diameter (LVEDd), 6-minute walk test (6MWT), left ventricular end-systolic volume (LVESV) and NYHA grading were improved (P<0.05), and QRS time limit was shortened significantly (P<0.05) in response group and super-response group after CRT. In non-response group, only NYHA grading was improved (P<0.05) and other indexes had no significant changes. Conclusion CRT-P/D can relieve the symptoms and improve prognosis. AF is an important factor of inadequate shocks and lower pacing rate, which maybe a major cause of decreased postoperation response.
Keywords：Heart failureCardiac resynchronization therapyAtrial fibrillation
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 846-850 )