Application value of coronary computed tomographic angiography and high sensitivity C-reactive protein ;in diagnosis in patients with acute coronary syndrome
SUN Shun-yang
SHAO Xue-song
QI Zheng-jun
SHI Yang-cheng
Abstract：Objective To investigate the application value of coronary computed tomographic angiography (CTA) of multiple spiral computed tomography (MSCT) and high sensitivity C-reactive protein (hs-CRP) in diagnosis in patients with acute coronary syndrome (ACS). Methods ACS patients (n=80) were given examinations of coronary CTA and coronary angiography (CAG), and the results of CAG was compared with those of coronary CTA. The level of serum hs-CRP was detected by using immunoturbidimetry in patients with varying coronary stenosis degrees. Results A total 320 vessels were detected by CAG and CTA, and 68 vessels without stenosis, 152 with mild stenosis, 68 with moderate stenosis and 32 with severe stenosis were detected by CTA, and 74 without stenosis, 160 with mild stenosis, 59 with moderate stenosis and 27 with severe stenosis detected by CAG (P>0.05). A total 252 stenosis vessels were detected by coronary CTA, and the detective stenosis rates of left main stem, left anterior descending vessel, circumflex vessel and right coronary artery had no statistical significance compared with those detected by CAG (P>0.05). Coronary CTA detected 215 (85.32%) soft plaques, which had no statistical significance compared with those (206, 81.75%) detected by CAG (P>0.05). The level of hs-CRP was significantly higher in 3-vessel lesion group than that in 1-vessel lesion group and 2-vessel lesion group (P<0.05), and significantly higher in 2-vessel lesion group than that in 1-vessel lesion group (P<0.05). Conclusion The diagnostic results of coronary CTA is highly similar to those of CAG in ACS patients, but CTA has non-invasive advantage. Coronary CTA combining hs-CRP has more significant value in clinic in diagnosis of ACS.
Keywords：High sensitivity C-reactive proteinAcute coronary syndromeCoronary angiography
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 836-838,842 )