Clinical correlative factors of left ventricular end-diastolic pressure in patients with acute non-ST-segment elevation myocardial infarction
ZHOU Xia
ZHOU Shao-bo
LI Guo-qing
JIN Yuan-zhe
ZHOU Dong-hui
WANG Yong
LIU Jing
WANG Qi
Abstract：Objective To investigate the correlative factors influencing left ventricular end-diastolic pressure (LVEDP) in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI). Methods NSTEMI patients undergone PCI (n=84) were chosen from Jan. 2010 to May 2014, and divided, according to LVEDP before left ventricular angiography, into group A (LVEDP≤15 mmHg, n=36) and group B (LVEDP>15 mmHg, n=48). The changes of N-terminal pro brain natriuretic peptide (NT-proBNP), cardiac troponin T (cTnT) and creatine kinase MB (CK-MB) were observed before and after PCI, and LVEDd, LAEDd, RV and LVEF were detected by using echocardiogram. LVEDP was detected by using left heart catheterization before PCI. The patients were given examination of left ventricular angiography and coronary Gensini scoring. Results There was significant difference in age, sex, percentages of cases of Killip grade II or higher and abnormal ventricular motion, NT-proBNP, LVEF, coronary Gensini scores and duration from disease attack to crime vessel open between group A and group B (P<0.05). LVEDP was significantly higher in patients with left main coronary artery as crime vessel than that in ones with other coronary artery disease (P<0.05). The duration from disease attack to crime vessel open, NT-proBNP, coronary Gensini scores and LVEF were risk factors for LVEDP. Conclusion The duration from disease attack to crime vessel open, NT-proBNP, coronary Gensini scores and LVEF are closely related to the increase of LVEDP in NSTEMI patients, which is significant to patient’s prognosis.
Keywords：Non-ST-segment elevation myocardial infarctionLeft ventricular end-diastolic pressureGensini score
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 780-783,786 )