Reviews on characteristics of coronary artery in elderly patients with chest pain and with or without diabetes mellitus by applying computed tomography
WANG Xiu-jie
ZENG Fan-ben
CHEN Wen
MA Jin-ling
Abstract：Objective To review the characteristics of coronary artery lesion and atherosclerotic plaque by applying coronary computed tomography angiography (CCTA) in elderly patients with chest pain and with or without diabetes mellitus (DM).Methods The patients with chest pain (n=488, aged over 60) undergone 64-row CCTA scanner were chosen from Jan. 2012 to Dec. 2014, including 221 with DM (DM group) and 267 without DM (non-DM group). The distribution and type characteristics of coronary plaque were compared in 2 groups. The survival rate and prognosis of acute coronary syndrome events were observed after followed up for 1 y.Results The incidences of multi-vessel lesion (75.1%) and diffuse lesion (43.9%) of coronary artery were significantly higher in DM group than those in non-DM group (37.8%, 16.1%), and incidence of mixed plaque was higher in DM group than that in non-DM group (82.4%vs. 39.7%). The occurring rate of coronary stenosis (over 50% and over 75%) was higher in DM group (61.5%, 31.2%) than that in non-DM group (36.0%, 19.9%). Kaplan-Meier survival curve showed that the survival rate of acute coronary syndrome events in patients with coronary stenosis over 50% was significantly lower in DM group than that in non-DM group (P<0.05) after followed up for 1 y.Conclusion CCTA can accurately reflect the difference in atherosclerotic plaques between patients with or without DM, which is helpful to review early risk of cardiovascular events.
Keywords：Coronary computed tomography angiographyAtherosclerotic plaqueDiabetes mellitusElderly people
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 693-695 )