Influence of arotinolol on anxiety and depression in patients with hypertension
LIU Chun-ping
LUO Li
TAN Bo
YI Gui-yan
LI Jun-xia
Abstract：Objective To observe the influence of arotinolol on anxiety and depression in patients with primary hypertension.Methods The middle-aged and young patients with grade 1 or grade 2 primary hypertension (n=100, male 62, female 38, aged from 19 to 60 and average age=40.2±10.8) were chosen from Jan. 2014 to Jun. 2014. All patients were randomly divided into arotinolol group and amlodipine group (eachn=50) and were given drugs for 8 w continuously. The changes of 24 h ambulatory blood pressure (BP) and heart rate (HR) recorded, and depression and anxiety levels were reviewed by using Beck Depression Inventory and state-anxiety inventory (S-AI).Results BP decreased in 2 groups after treatment (allP<0.05). HR decreased significantly in arotinolol group compared with amlodipine group [(77.8±11.0) time/minvs. (67.5±10.0) time/min] after treatment (P<0.05). The level of anxiety decreased in arotinolol group compared with amlodipine group [(37.9±10.2)vs. (35.2±7.6), P<0.05].Conclusion Arotinolol can reduce the level of anxiety at the same time of decreasing BP effectively in hypertensive patients.
Keywords：ArotinololAmlodipineAnxietyDepression
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 676-678 )