Significance of serum cystantin C in prognostic review in patients with acute myocardial infarction
ZHAO Lei
ZHENG Ye
WANG Yun-fei
SHENG Ji-zhang
CAO Xu-fen
Abstract:Objective To discuss the significance of serum cystantin C (Cys-C) in short-term or long-term prognostic reviews in patients with acute myocardial infarction (AMI).Methods The patients with AMI diagnosed for the first time (n=533, male 418 and female 115) were chosen from Jan. 2009 to Oct. 2013. All patients were divided, according to Cys-C level 24 h after hospitalization, into control group (n=200, Cys-C<17 mg/L) and test group (n=333, Cys-C>1.17 mg/L). The level of serum Cys-C was detected in all patients within 24 h after hospitalization. After the patients were discharged from hospital, they were followed up by telephone for 1 y. The study end was major adverse cardiovascular events (MACE).Results The all-cause mortality was higher in test group than that in control group (10.8%vs. 4.5%) during hospital stay (P<0.05). The follow-up for 1 y showed that non-event survival rate was lower in test group than that in control group (82.3%vs. 88.3%,P=0.007). The difference in mortality (4.3%vs. 3.6%), rate of re-revascularization (3.9%vs. 4.0%) and severe heart failure (2.7%vs. 2.5%) had no statistical significance (allP>0.05) between 2 groups.Conclusion The level of serum Cys-C is important in reviewing the short-term and long-term prognosis in AMI patients.
Keywords:Cystantin CAcute myocardial infarctionLong-term prognosis
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:2( 672-673 )