Radionuclide myocardial perfusion imaging in diagnosis of coronary artery restenosis after percutaneous coronary intervention：a Meta-analysis
LIU Zheng
CHEN Jin-liang
YU Wei-guo
REN Yong-mei
SONG Ming-hui
LI An-jun
LI Xiao-zhu
Abstract：Objective To review the efficacy of single photon emission computed tomography myocardial perfusion imaging (SPECT MPI) in diagnosis of coronary artery restenosis after percutaneous coronary intervention (PCI) through Meta-analysis.Methods The databases of PubMed, HighWire, CBMdisc, EMbase, CNKI, WanFang Database, VIP Database and superstar database were retrieved for collecting published documents related to coronary restenosis after PCI diagnosed by SPECT-MPI. All documents were screened according to inclusion and exclusion criteria to extract effect indicator data, and analyzed by using Meta-Disc1.4 software and Sata12.0 software. The effect indicators were weightedly merged, SROC curve and funnel plot were drawn, AUC and Q* index were calculated, and publication bias was tested further.Results There were totally 10 documents, 750 sample cases and 855 diseased coronary branches. When taking patients as research objects, there were 6 documents included involving 360 cases. The sensitivity was 0.88 (95%CI: 0.83~0.92), specificity was 0.83 (95%CI:0.77~0.89), AUC was 0.92 and Q* index was 0.85. When taking coronary artery as research objects, there were 8 documents included involving 763 coronary branches. The sensitivity was 0.86 (95%CI: 0.82~0.90), specificity was 0.89 (95%CI: 0.86~0.92), AUC was 0.94 and Q* index was 0.88.Conclusion MPI is highly effective in diagnosis of coronary restenosis, which can guide the making of clinical treatment plan.
Keywords：Myocardial perfusion imagingPercutaneous coronary interventionCoronary arteryRestenosisMeta-analysis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 605-608 )