Risk factors of major adverse cardiovascular events and deep vein thrombosis in patients undergoing total hip joint replacement
SONG Wei
HUANG Zhi-bin
Abstract：Objective To discuss the risk factors of major adverse cardiovascular events (MACE) and deep vein thrombosis (DVT) in patients undergoing total hip joint replacement (THR). Methods The elderly patients with femoral neck fracture and first-time THR (n=117, male 49, female 68, aged from 60 to 92 and average age=69.4±8.1) were chosen from Jan. 2009 to Oct. 2013. The risk factors of MACE and DVT were analyzed 30 d after THR. Results Among all patients, there were 33 with ASA grade I, 49 with ASA grade II, 29 with ASA grade III and 6 with ASA grade IV. There were 80 cases with local anesthesia and 37 with general anesthesia. There were 38 cases with transfusion volume from 1 u to 2 u and 42 with transfusion volume>2 u during THR. There were 8 cases (6.83%) with MACE, 12 (10.26%) with DVT and 5 (4.27%) died. The risk of MACE increased in patients with age>80 (OR=13.418, 95%CI:1.201~149.916), preoperative ASA grade III and ASA grade IV (OR=18.782, 95%CI:1.478~238.714) and complicating heart failure (OR=20.144, 95%CI:1.094~370.942), and risk of DVT increased in patients with age>80 (OR=2.392, 95%CI:1.179~4.856). Conclusion The risk of MACE increases in patients with age>80, preoperative ASA grade III, ASA grade IV and complicating heart failure 30 d after THR, and risk of DVT increases in patients with age>80 after THR.
Keywords：Total hip joint replacementElderly patientsPerioperative periodRisk prevention research
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 490-492 )