Acupuncture therapies for intervening dyslipidemia：a summary overview on systematic reviews and Meta-analysis

CHEN Hao; WANG Yan; HU Xuan-ming; XU Wen-tao; GU Yi-huang

doi:10.3969/j.1674-4055.2015.04.02

Abstract：Objective To conduct a summary overview on systematic reviews and Meta-analysis of acupuncture therapies for intervening dyslipidemia. Methods The databases of PubMed, Embase, Cochrane Library, CBM, CNKI and WanFang Database were retrieved for searching the studies on systematic reviews and Meta-analysis of acupuncture therapies for intervening dyslipidemia. The methodological quality of included studies was reviewed by using AMSTAR tools, and grades of evidence were reviewed by using GARDE system. Results There was finally only 1 eligible study included, which compared acupuncture therapy and medication therapy. The results of AMSTAR tools (totally 11 items) showed that in item 1, the study did not provide registration information and study proposal. In item 2, the study did not give reviewers’ information although it introduced there were 2 reviewers for separated reviewing. In item 10 and item 11, the study did not review publication bias and explain relevant interest conflicts during reviewing procedure. In other 7 items, the study described well. The quality grade reviewing of GRADE system showed that the quality of evidence was reduced due to risk of bias, inconsistency, indirection, precision and publication bias. The quality of evidence was at very low grade because risk of bias, inconsistency and publication bias after reviewing 10 outcome indicators focused by the study. Conclusion The quantity of systematic reviews of acupuncture therapy for dyslipidemia are smaller now, methodological quality is lower, and grade of evidence is very low, so the therapy should be applied cautiously in clinic practice.