Pharmacotherapy and mental intervention in heart failure patients with anxiety and depression after cardiac ;resynchronization therapy
TIAN Fu-li
LU Chuan-dong
LI Xue-yong
ZHANG Er-jian
ZHANG Bin
BU Xue-qin
GU Xiao-li
ZHANG Yan-ping
Abstract：Objective To investigate the influences of pharmacotherapy and mental intervention on anxiety and depression in heart failure patients after treating with cardiac resynchronization therapy (CRT). Methods The heart failure patients (n=40) with anxiety and depression after treated with cardiac resynchronization therapy (CRT) were reviewed by using Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA). All patients were randomly divided into observation group and control group (each n=20). After 6 m, the levels of anxiety and depression, incidence of sudden death, angina pectoris, myocardial infarction and ventricular tachycardia, and 6-minute walk test (6MWT), LVEF and LVEDd were reviewed and compared in 2 groups. Results In observation group, 6MWT [(540±13.2) m vs. (380±18.5) m], LVEF [(45.31±3.45)%vs. (39.25±4.25)%] and LVEDd [(50.2 ±6.42) mm vs. (59.3±7.12) mm] were significantly higher than those in control group. The incidence of sudden death, angina pectoris, myocardial infarction and ventricular tachycardia was significantly lower in observation group than those in control group (P<0.05). The status of anxiety and depression was relieved more significant in observation group compared with control group (P<0.01). Conclusion The efficacy of pharmacotherapy and mental intervention is higher than that of routine therapy in heart failure patients after CRT.
Keywords：Cardiac resynchronization therapyAnxietyDepressionMental interventionDrugsHeart failure
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 394-395,399 )