Predictive value of microvolt T wave alternans to ventricular arrhythmia in patients with ischemia heart disease
LIU Ze-jun
LI Wan-zhen
ZENG Yi-wen
LU Shui-ying
YANG Cheng
CHEN Li-xing
RUAN Qu-wen
Abstract：Objective To discuss the predictive value of microvolt T wave alternans (TWA) to risk of ventricular arrhythmia in patients with ischemia heart disease. Methods The patient (n=100) were chosen from Jan. 2012 to Nov. 2013, and given TWA examination. All patients were divided, according to the outcomes of TWA, into positive TWA group (n=53) and negative TWA group (n=47), and other 50 cases with normal outcomes of ECG, chest X-ray and myocardial contrast echocardiography were chosen as control group. All groups were given ECG monitoring during hospitalization. After patients were discharged from hospital, they were followed up for 1 y and then given re-examination with Holter for observing the incidence of ventricular arrhythmias. Results The comparison in heart rate, heart function and LVEF had no statistical difference between positive TWA group or negative TWA group and control group (P<0.05). There was no case with ventricular arrhythmias in control group, and incidence of ventricular arrhythmias was 84.91%in positive TWA group and 48.94%in negative TWA group (P<0.05). The sensitivity of TWA for predicting ventricular arrhythmias was 66.17%, specificity was 75.0%, positive predicted value was 84.91%, and negative predicted value was 51.06%. Conclusion Positive TWA is closely correlated to incidence of ventricular arrhythmias in patients with ischemia heart disease, which has certain predictive value.
Keywords：Microvolt T wave alternansIschemia heart diseaseVentricular arrhythmiaPredictive study
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 387-389 )