Prognosis in patients with acute ischemic cerebral apoplexy and different blood pressure levels

LI Hong; YANG Yan-zhu; LIU Fu-da; CHEN Shi-wen; LI Chao-ying

doi:10.3969/j.1674-4055.2015.03.27

Abstract：Objective To analyze the prognosis in patients with acute ischemic cerebral apoplexy and different levels of blood pressure (BP). Methods The patients diagnosed for the first time (n=197, male 111, female 86, aged from 43 to 81 and average age=63.71±8.54) were chosen from June 2012 to June 2014, and then divided, according to their admission BP levels, into group A (n=47, BP≤140/90 mmHg), group B (n=99, SBP from 141 mmHg to 160 mmHg and DBP from 91 mmHg to 100 mmHg), group C (n=36, SBP from 161 mmHg to 180 mmHg and DBP from 101 mmHg to 110 mmHg) and group D (n=15, BP>180/110 mmHg). The level of BP and NIHSS scores were monitored at hospitalization time, and 10 d and 30 d after admission. Results The comparison in NIHSS scores showed that NIHSS scores were significantly higher in group C and group D than those in group A and group B (all P<0.05), which meant when SBP>160 mmHg, NIHSS scores increased significantly. After admission for 10 d, there were 20 cases died in total 197 patients and the mortality was 10.15%, and the mortality was higher in group D than that in group A, group B and group C [(53.33%vs. 4.26%), (53.33%vs. 7.07%), (53.33%vs. 8.33%), all P<0.05]. The comparison in NIHSS scores showed that NIHSS scores were still higher in group C and group D than those in group A and group B (all P<0.05) after admission for 10 d. At the same time, BP level was recovered to normal in group A and group B. After admission for 30 d, the comparison in NIHSS scores showed that NIHSS scores were significantly higher in group D than those in other groups (all P<0.05). Conclusion The level of BP will increase and prognosis will be poor in the patients with acute ischemic cerebral apoplexy. They should be given reasonable antihypertensive therapy for improving prognosis and quality of life.