Correlation among sex hormones, blood fat and high-sensitivity C-reactive protein in male patients with acute coronary syndrome

LI Xiu-mei; XU Peng

doi:10.3969/j.1674-4055.2015.02.27

Abstract：Objective To investigate the correlation among sex hormones, blood fat and high-sensitivity C-reactive protein (hs-CRP) in male patients with acute coronary syndrome (ACS).Methods Male patients (n=284, aged from 50 to 80) hospitalized due to chest oppression and chest pain were chosen from Mar. 2012 to Oct. 2012. All patients were divided, according to outcomes of coronary angiography (CAG), into acute coronary syndrome group (ACS group,n=97), stable angina pectoris group (SAP group,n=105) and non-CHD group (n=82). The outcomes of CAG showed that coronary artery lesion included 3-vessel lesion, 2-vessel lesion and 1-vessel lesion. The levels of blood fat, testosterone and hs-CRP were detected and correlation among these indexes was analyzed.Results The levels of testosterone and triglyceride (TG) increased (allP<0.05), and hs-CRP level decreased (P<0.01) in SAP group compared with ACS group. The levels of testosterone and TG increased and hs-CRP level decreased in non-CHD group compared with ACS group (allP<0.01). The levels of total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and testosterone increased, and hs-CRP level decreased in non-CHD group compared with SAP group (allP<0.05). The level of testosterone was not correlated to levels of blood fat and hs-CRP (allP>0.05). The level of testosterone had no statistical difference in patients with 1-vessel lesion, 2-vessel lesion or 3-vessel lesion (allP>0.05).Conclusion The level of testosterone decreases and hs-CRP level increases in male patients with ACS. The correlation has not been found among testosterone, blood fat and hs-CRP. There is no statistical difference in patients with different severity of coronary lesion.