Influences of cardiopulmonary bypass-coronary artery bypass grafting and off-pump coronary artery bypass grafting on level of brain natriuretic peptide
YANG Lei-lei
ZHANG Hong-chao
Abstract：Objective To investigate the influences of cardiopulmonary bypass-coronary artery bypass grafting (CPB-CABG) and off-pump coronary artery bypass grafting (OPCABG) on heart function.Methods The patients (n=40, female 14 and male 26) were chosen from June 2013 to Oct. 2014, and randomly divided into CPB-CABG group and OPCABG group (eachn=20). The plasma samples were collected for detecting level of brain natriuretic peptide (BNP) 1 d before surgery and 12 h, 24 h and 36 h after surgery.Results The level of plasma BNP increased significantly in 2 groups 12 h, 24 h and 36 h after surgery (allP<0.05). The level of BNP increased after 12 h [(138.0±42.6) pg/mLvs. (266.0±52.1) pg/mL], 24 h [(258.0±38.3) pg/mLvs. (488.0±56.7) pg/mL] and 36 h [(186.0±43.6) pg/mLvs. ( 356.0±47.1) pg/mL] in CPB-CABG group compared with OPCABG group (all P<0.05).Conclusion OPCABG has less effect on heart function than CPB-CABG.
Keywords：Coronary artery bypass graftingbrain natriuretic peptideCoronary heart disease
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 235-236,239 )