Relationship between left ventricular restrictive filling dysfunction and risk of new-onset atrial fibrillation after acute myocardial infarction
ZHAO Yu-ying
WEI Ya-li
DING Chao
QI Shu-ying
SUN Jia-an
WANG Dong-mei
Abstract：Objective To study the relationship between left ventricular restrictive filling dysfunction and risk of new-onset atrial fibrillation (AF) after acute myocardial infarction (AMI).Methods The data of 288 AMI patients were retrospectively analyzed, and all patients were given echocardiogram examination within 1 d to 3 d after hospitalization and then divided into AF group and non-AF group. The data of sex, age, infarction position, NYHA grading, risk factor, number of diseased coronary vessels, drug administration, LVEF, LVEDd and ratio of E/A were compared between 2 groups. The relationship between clinical or echocardiogram parameters and new-onset AF were given single factor and multi-factor Logistic regression analysis.Results The incidence of new-onset AF was 14.2% (42/288) in all included patients. The percentages of female patients and patients with Killip≥Ⅱ, left ventricular restrictive filling dysfunction and 3-vessel lesion, average age, LVEDd, diuretics usage rate were all higher in AF group than those in non-AF group (P<0.05 toP<0.01). Logistic regression analysis found that age>65 (OR=2.28, 95%CI: 1.78~4.97), LVEDd>40 mm (OR=1.71, 95%CI: 1.13~2.86), Killip≥Ⅱ (OR=1.49, 95%CI:1.03~1.74) and left ventricular restrictive filling dysfunction (OR=2.58, 95%CI: 1.64~3.75) were independent risk factors of new-onset AF.Conclusion Left ventricular restrictive filling dysfunction is a independent risk factor of new-onset AF of AMI.
Keywords：Acute myocardial infarctionAtrial fibrillationLeft ventricular diastolic dysfunctionLeft ventricular restrictive filling dysfunction
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 225-228 )