Curative effect of Guanxin Shutong Capsules on psychocardiacology in patients with chronic stable ;angina pectoris (syndrome of heart blood stasis)
ZHAO Kang
MENG Kang
GE Chang-jiang
LV Shu-zheng
Abstract：Objective To review the curative effect of Guanxin Shutong Capsules on psychocardiacology in patients with chronic stable angina pectoris (SAP, syndrome of heart blood stasis).Methods SAP patients (n=134) were chosen from wards or out-patient department, and randomly divided into test group (n=67) and control group (n=65). The control group was given routine therapy of Western medicine and test group was given Guanxin Shutong Capsules (3 capsules, tid) based on routine therapy of Western medicine. All patients were observed and followed up for 4 w. The amelioration of AP and TCM symptoms were reviewed in all groups. The patients were given anxiety and depression reviews by using self-rating anxiety scale (SAS) and self-rating depressive scale (SDS) before and after treatment, and adverse reactions were recorded.Results The total effective rate of AP amelioration and that of TCM symptom amelioration were significantly improved in test group compared with control group (83.6%vs. 63.1%,P<0.05; 89.6%vs. 72.3%,P<0.05). The incidence of anxiety or depression and symptom scores decreased significantly in test group compared with control group (SAS decrease value: 15.57±15.77vs. 7.06± 20.80,P<0.05; SDS decrease value: 13.58±14.76vs. 6.46±16.65,P<0.05). The gastrointestinal adverse reactions increased in test group compared with control group (17.9%vs. 6.0%,P<0.05), and there was no gastrointestinal bleeding observed in 2 groups.Conclusion Guanxin Shutong Capsules has reliable curative effect on SAP (syndrome of heart blood stasis), which at the same time can ameliorate anxiety and depression symptoms and play a role of treating psychocardiacology with higher safety.
Keywords：Guanxin Shutong CapsulesStable angina pectorisPsychocardiacology
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 184-187 )