Predictive value of fibrillatory wave amplitude on lead V1 of surface electrocardiography to effectiveness of radiofrequency ablation on persistent atrial fibrillation
TAN Chen
XU Wei
HU Xue-hong
CHEN Nian
SHI Hong-ling
LIU Jian-guo
CUI Jun-yu
LI Jun-xia
Abstract：Objective To review the predictive value of fibrillatory wave (f-wave) amplitude on lead V1 of surface electrocardiography (ECG) to effectiveness of radiofrequency ablation on persistent atrial fibrillation (AF). Methods The patients (n=49) were chosen from Mar. 2010 to Dec. 2013 and divided into non-recurrence group (n=33) and recurrence group (n=16) according to results of follow-up, and also divided into atrial flutter (AFL) group (n=10) and non-AFL group (n=39) according to whether AF transferring to AFL after pulmonary vein isolation during radiofrequency ablation. The maximum amplitude and mean amplitude of f-wave on lead V1 of surface ECG were detected and compared among all groups, and predictive value of f-wave to AF recurrence and AFL transferring was reviewed. Results Compared with non-recurrence group, the maximum amplitude [(0.150 ±0.519) mV vs. (0.094±0.480) mV] and mean amplitude [(0.125±0.50) mV vs. (0.077±0.032) mV] of f-wave on V1 lead decreased in recurrence group (all P<0.01). The ROC curves of the maximum amplitude and mean amplitude showed area under curve (AUC) was, respectively, 0.77 (P=0.002) and 0.80 (P=0.001). The cut-off value of the maximum amplitude for predicting recurrence was 0.115 mV and sensitivity was 75.8%and specificity was 68.7%, and mean amplitude was 0.094 mV and sensitivity was 78.8%and specificity was 68.7%. Compared with AFL group, the mean amplitude of f-wave on V1 lead decreased [(0.139±0.052) mV vs. (0.102±0.047) mV] in AFL group (P<0.05). The ROC curves of mean amplitude showed AUC was 0.71 (P<0.05). The cut-off value of the mean amplitude for predicting AFL transforming was 0.109 mV, and sensitivity was 60%and specificity was 61.5%. Conclusion The amplitude of f-wave on V1 lead is correlated to persistent AF recurrence after radiofrequency ablation, and the possibility of recurrence is lower in the patients with higher amplitude.
Keywords：Persistent atrial fibrillationSurface electrocardiographyFibrillatory wave amplitudeCatheter radiofrequency ablationRecurrence
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 87-90 )